In addition, astrocytes, which normally support neurons, become dysfunctional through a process called astrogliosis, which worsens glutamate imbalance and reduces neuronal support (Boille et al., 2006)
Endocrine regulation of muscle remodeling and lipid infiltration. J Cachexia Sarcopenia Muscle
Key benefits for perimenopausal women: Supports faster repair of tendons, ligaments, and muscle tissue that become more injury-prone as estrogen falls Reduces local inflammation through macrophage M1-to-M2 polarization, which may ease joint pain and soft-tissue discomfort common in perimenopause Promotes angiogenesis via endothelial cell migration and tube formation, improving blood supply to areas of chronic or recurring injury Administration method: Subcutaneous injection, typically into the abdomen with rotating injection sites
doi: 10.1111/j.1468-1293.2010.00906.x 147 FalutzJAllasSBlotKPotvinDKotlerDSomeroMet al
Avoid contact with eyes and discontinue if irritation persists